Aurantio‐Obtusin Suppresses Airway Inflammation and Serum ICAM‐1 Expression in Guinea Pig Allergic Asthma Model
Overall, the data suggests that aurantio-obtusin mitigated ovalbumin-induced airway inflammation by impeding the production of OVAsIgE and suppressing levels of key pro-inflammatory cytokines. Our findings suggest that aurantio-obtusin has potential benefits in the management of allergic airway inflammation in type 2 asthma.
Authors
- Benjamin Obukowho Emikpe (ORCID: https://orcid.org/0000-0003-2458-6504)
- Aaron Opoku Antwi (ORCID: https://orcid.org/0000-0001-9713-9487)
- Cynthia Amaning Danquah (ORCID: https://orcid.org/0000-0003-4287-856X)
- Newman Osafo (ORCID: https://orcid.org/0000-0001-8142-2368)
- Mavis Sersah Nyarko
Institutions
- Kwame Nkrumah University of Science and Technology (GH)
Publication Details
- Journal
- Immunity Inflammation and Disease
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1002/iid3.70160
- Primary Topic
- Mast cells and histamine
- Type
- article
- Field-Weighted Citation Impact
- 0.00