Carnitine supplementation improves insulin sensitivity and skeletal muscle acetylcarnitine formation in patients with type 2 diabetes
Carnitine supplementation improved insulin sensitivity and tended to lower IHL and fasting plasma glucose levels in patients with type 2 diabetes. Furthermore, carnitine supplementation increased acetylcarnitine concentration in muscle, which may underlie the beneficial effect on insulin sensitivity.
Authors
- Gert Schaart (ORCID: https://orcid.org/0000-0003-4259-9528)
- Riekelt H. Houtkooper (ORCID: https://orcid.org/0000-0001-9961-0842)
- Yvo J.M. Op den Kamp
- Esther Kornips
- Joachim Ernst Wildberger (ORCID: https://orcid.org/0000-0002-4810-6854)
- Rubén Zapata‐Pérez (ORCID: https://orcid.org/0000-0003-4432-9652)
- Bas Havekes
- Ashraf Virmani (ORCID: https://orcid.org/0000-0003-1216-6393)
- Esther Phielix
- Vera B. Schrauwen‐Hinderling (ORCID: https://orcid.org/0000-0001-7795-584X)
- Pandichelvam Veeraiah (ORCID: https://orcid.org/0000-0002-9149-7483)
- Patrick Schrauwen (ORCID: https://orcid.org/0000-0002-0973-847X)
- Matthijs K. C. Hesselink (ORCID: https://orcid.org/0000-0003-3084-0687)
- Yvonne M. H. Op den Kamp‐Bruls
- Bart R. B. Berendsen
Institutions
- Leiden University Medical Center (NL)
- Maastricht University (NL)
- Amsterdam University Medical Centers (NL)
- Deutsches Diabetes-Zentrum e.V. (DE)
- German Center for Diabetes Research (DE)
- Heinrich Heine University Düsseldorf (DE)
- University of Amsterdam (NL)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1111/dom.16298
- Citations
- 6
- Primary Topic
- Diet and metabolism studies
- Type
- article
- Field-Weighted Citation Impact
- 6.99
Funders
- Amsterdam University Medical Centers
- Universiteit Maastricht
- Maastricht Universitair Medisch Centrum
- Topconsortium voor Kennis en Innovatie