Comparing Long‐Term Infliximab Persistence Following a Switch to a Biosimilar in Patients With Inflammatory Bowel Disease: No Cause for Concern

Long-term infliximab persistence was similar between switch and nonswitch cohorts over 4 years of follow-up. These data represent the longest duration of "real-world" follow-up, and should provide further reassurance that nonmedical switching is safe and clinically comparable to ongoing originator infliximab in clinically stable patients with IBD.

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Publication Details

Journal
Journal of Gastroenterology and Hepatology
Published
2025-02-27
DOI
https://doi.org/10.1111/jgh.16916
Primary Topic
Biosimilars and Bioanalytical Methods
Type
article
Field-Weighted Citation Impact
0.00

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article

Comparing Long‐Term Infliximab Persistence Following a Switch to a Biosimilar in Patients With Inflammatory Bowel Disease: No Cause for Concern

Thomas Skinner, Craig Haifer, Ashish Srinivasan, Daniel R. van Langenberg et al.
Journal of Gastroenterology and Hepatology
Biosimilars and Bioanalytical Methods
article

Comparing Long‐Term Infliximab Persistence Following a Switch to a Biosimilar in Patients With Inflammatory Bowel Disease: No Cause for Concern

Thomas Skinner, Craig Haifer, Ashish Srinivasan, Daniel R. van Langenberg, Simon Ghaly, Lena Thin, Shankar Menon, James Winston, Angus W. Jeffrey, Yoon‐Kyo An, Richard Fernandes, Paulina Suo, Nicholas Olsen
article en

Abstract

Long-term infliximab persistence was similar between switch and nonswitch cohorts over 4 years of follow-up. These data represent the longest duration of "real-world" follow-up, and should provide further reassurance that nonmedical switching is safe and clinically comparable to ongoing originator infliximab in clinically stable patients with IBD.

Journal of Gastroenterology and HepatologyVol. 40(5)
The University of Queensland (AU), The University of Western Australia (AU), Royal Perth Hospital (AU), Fiona Stanley Hospital (AU), UNSW Sydney (AU), St Vincent's Hospital Sydney (AU), Mater Research (AU), Eastern Health (AU), St Vincent’s Private Hospital Sydney (AU), Mater Adult Hospital (AU), Monash University (AU)
University of New South Wales
Openalex Percentile: Top 96%
Biosimilars and Bioanalytical Methods
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Comparing Long‐Term Infliximab Persistence Following a Switch to a Biosimilar in Patients With Inflammatory Bowel Disease: No Cause for Concern — Thomas Skinner, Craig Haifer, et al. · Journal of Gastroenterology and Hepatology (2025) | TGRS Research Map | TGRS