<scp>ACT001</scp> Suppresses the Malignant Progression of Small‐Cell Lung Cancer by Inhibiting Lactate Production and Promoting Anti‐Tumor Immunity
ACT001 inhibits the malignant progression of SCLC by suppressing lactate production, modulating macrophage polarization, and restraining tumor metastasis through PGK1 targeting.
Authors
- Tingting Qin (ORCID: https://orcid.org/0000-0002-1975-9696)
- Dingzhi Huang (ORCID: https://orcid.org/0000-0002-2798-9459)
- Xin Ding (ORCID: https://orcid.org/0000-0002-1563-3367)
- Yaxin Lu (ORCID: https://orcid.org/0000-0001-6278-4347)
- Xiaonan Xi
- Wenjing Wang (ORCID: https://orcid.org/0000-0003-1172-0700)
- Yue Chen (ORCID: https://orcid.org/0000-0001-8888-1452)
- Jingya Wang (ORCID: https://orcid.org/0000-0002-4371-4674)
- Ting Mei (ORCID: https://orcid.org/0000-0002-5130-0025)
Institutions
- Nankai University (CN)
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- Thoracic Cancer
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1111/1759-7714.70028
- Primary Topic
- Lung Cancer Research Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Nankai University
- Natural Science Foundation of Tianjin City