<scp>EAACI</scp> Guidelines on Environmental Science for Allergy and Asthma—Recommendations on the Impact of Indoor Air Pollutants on the Risk of New‐Onset Asthma and on Asthma‐Related Outcomes

The EAACI Guidelines used the GRADE approach to evaluate the impact of major indoor air pollutants (dampness and mould, cleaning agents, volatile organic compounds and pesticides) on the risk of new-onset asthma and on asthma-related outcomes. The guideline also acknowledges the synergies among indoor air pollutants and other components of the indoor exposome (allergens, viruses, endotoxins). Very low to low certainty of evidence was found for the association between exposure to indoor pollutants and increased risk of new-onset asthma and asthma worsening. Only for mould exposure there was moderate certainty of evidence for new-onset asthma. Due to the quality of evidence, conditional recommendations were formulated on the risk of exposure to all indoor pollutants. Recommendations are provided for prevention, patient care and mitigation in a framework supporting rational decisions for healthcare professionals and patients to individualize and improve asthma management. For policymakers and regulators this evidence-informed guideline supports setting legally binding standards and goals for indoor air quality at international, national and local levels. Asthma management counselled by the current EAACI guidelines can improve asthma-related outcomes but community and governmental measures for improved indoor air quality are needed to achieve significant impact.

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Publication Details

Journal
Allergy
Published
2025-02-28
DOI
https://doi.org/10.1111/all.16502
Citations
14
Primary Topic
Air Quality and Health Impacts
Type
article
Field-Weighted Citation Impact
16.80
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article

EAACI Guidelines on Environmental Science for Allergy and Asthma—Recommendations on the Impact of Indoor Air Pollutants on the Risk of New‐Onset Asthma and on Asthma‐Related Outcomes

Claudia Traidl‐Hoffmann, Santiago Quirce, Kari Christine Nadeau, Ioana Agache et al.
14 citations
Allergy
Air Quality and Health Impacts
16.80
article

EAACI Guidelines on Environmental Science for Allergy and Asthma—Recommendations on the Impact of Indoor Air Pollutants on the Risk of New‐Onset Asthma and on Asthma‐Related Outcomes

Claudia Traidl‐Hoffmann, Santiago Quirce, Kari Christine Nadeau, Ioana Agache, Lorenzo Cecchi, Carmen Galán, Kian Fan Chung, Jolanta Walusiak‐Skorupa, Magdalena Zemelka‐Wiącek, Isabella Annesi‐Maesano, Benedetta Biagioni, Mohamed F. Jeebhay, Stefanie Gilles, Cezmi A. Akdiş, Marek Jutel, Gennaro D’Amato, Stefano R. Del Giacco, Athanasios Damialis, Stephen T. Holgate, J. Sastre, Stelios Kazadzis, Nikolaos G. Papadopoulos, Javier Domínguez Ortega
article en
14 citations

Abstract

The EAACI Guidelines used the GRADE approach to evaluate the impact of major indoor air pollutants (dampness and mould, cleaning agents, volatile organic compounds and pesticides) on the risk of new-onset asthma and on asthma-related outcomes. The guideline also acknowledges the synergies among indoor air pollutants and other components of the indoor exposome (allergens, viruses, endotoxins). Very low to low certainty of evidence was found for the association between exposure to indoor pollutants and increased risk of new-onset asthma and asthma worsening. Only for mould exposure there was moderate certainty of evidence for new-onset asthma. Due to the quality of evidence, conditional recommendations were formulated on the risk of exposure to all indoor pollutants. Recommendations are provided for prevention, patient care and mitigation in a framework supporting rational decisions for healthcare professionals and patients to individualize and improve asthma management. For policymakers and regulators this evidence-informed guideline supports setting legally binding standards and goals for indoor air quality at international, national and local levels. Asthma management counselled by the current EAACI guidelines can improve asthma-related outcomes but community and governmental measures for improved indoor air quality are needed to achieve significant impact.

AllergyVol. 80(3)
Inserm (FR), University of Cape Town (ZA), University of Cagliari (IT), University of Augsburg (DE), Université de Montpellier (FR), National and Kapodistrian University of Athens (GR), Nofer Institute of Occupational Medicine (PL), Aristotle University of Thessaloniki (GR), University of Manchester (GB), Helmholtz Zentrum München (DE), Transylvania University of Brașov (RO), Wroclaw Medical University (PL), Nuovo Ospedale San Giovanni di Dio (IT), Centro de Investigación Biomédica en Red (ES), Physikalisch-Meteorologisches Observatorium Davos (CH), Harvard Global Health Institute (US), University of Southampton (GB), Imperial College London (GB), University of Córdoba (ES), Universidad Autónoma de Madrid (ES), University of Naples Federico II (IT)
Openalex Percentile: Top 1%
Air Quality and Health Impacts
16.80
DOIOpen Access PDFOpenAlex
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