Dupless: Toward a patient‐friendly approach for erectile dysfunction nature differentiation – a study of 291 penile duplex Doppler ultrasound assessments

The findings of this "Dupless" study highlight the limitations of relying solely on initial evaluation to differentiate ED etiology, stressing the need for additional diagnostic tools. While some predictive factors were identified, they proved insufficient for clinical use. Thus, an urgent need exists for the development of modern, noninvasive diagnostic tools to enhance ED classification. Future research could explore machine learning models to uncover complex patterns not evident in traditional statistical methods.