The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China

Distinct individual mutations, as well as multiple concurrent mutations, within EMB resistance-associated genes, contributed to variable levels of EMB resistance. These results have broadened our understanding of the molecular characteristics of EMB resistance in China.

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Publication Details

Journal
BMC Microbiology
Published
2025-03-01
DOI
https://doi.org/10.1186/s12866-025-03821-y
Citations
2
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
2.79
Controls
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article

The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China

Wei Wang, Kanglin Wan, Xiaochen Bo, Xiuqin Zhao et al.
2 citations
BMC Microbiology
Tuberculosis Research and Epidemiology
2.79
article

The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China

Wei Wang, Kanglin Wan, Xiaochen Bo, Xiuqin Zhao, Tongyang Xiao, Haican Liu, Guilian Li, Shiqiang Lin, Xueting Fan, Cheng Qian, Lili Zhao, Hao Hang, X. Nan, Machao Li
article en
2 citations

Abstract

Distinct individual mutations, as well as multiple concurrent mutations, within EMB resistance-associated genes, contributed to variable levels of EMB resistance. These results have broadened our understanding of the molecular characteristics of EMB resistance in China.

BMC MicrobiologyVol. 25(1)
Sun Yat-sen University (CN), Fifth Affiliated Hospital of Sun Yat-sen University (CN), National Institute for Communicable Disease Control and Prevention (CN), Beijing Center for Disease Prevention and Control (CN), Fujian Agriculture and Forestry University (CN)
Good health and well-being
Openalex Percentile: Top 12%
Tuberculosis Research and Epidemiology
2.79
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The implications of mutations in multiple genes associated with ethambutol resistance among multidrug-resistant tuberculosis isolates from China — Wei Wang, Kanglin Wan, et al. · BMC Microbiology (2025) | TGRS Research Map | TGRS