In the face of a rare foe: Aggressive angiomyxoma of the vulva – A case report and literature review

Angiomyxoma is a rare, benign mesenchymal tumor that predominantly occurs in the pelvic and perineal regions. This case report presents a unique instance of 7 × 5 cm angiomyxoma (AM) arising in the vulvar region. The patient underwent an incisional biopsy followed by a wide local excision. Histopathological examination and immunohistochemical staining confirmed the mesenchymal origin of the tumor. Follow-up examinations demonstrated no recurrence after 1 year of follow-up. This case highlights the rarity of vulvar AM and emphasizes the importance of considering such tumors in the differential diagnosis of vulvar masses. The discussion encompasses the clinical presentation, diagnostic challenges, and treatment modalities associated with vulvar AM, contributing to the existing literature on this infrequent entity.