CENPF interaction with PLA2G4A promotes glioma growth by modulating mTORC1 and NF-κB pathways
This study found that CENPF plays a key role in promoting tumorigenesis through its interaction with PLA2G4A. This study provides a theoretical foundation for advancing multi-targeted therapies in glioma and for developing strategies to overcome tumor drug resistance.
Authors
- Qiang Sun (ORCID: https://orcid.org/0000-0003-4766-5512)
- Xinglan Li (ORCID: https://orcid.org/0000-0001-9927-0091)
- Shuzhi Li
- Jian Zhang (ORCID: https://orcid.org/0000-0002-6558-791X)
- Junhong Li (ORCID: https://orcid.org/0000-0002-8141-6408)
- M. Zhang (ORCID: https://orcid.org/0000-0002-5408-7389)
- Fei Du (ORCID: https://orcid.org/0000-0002-7863-5351)
- Yanhao Cheng (ORCID: https://orcid.org/0009-0007-1180-963X)
Institutions
- Capital Medical University (CN)
- Linyi People's Hospital (CN)
- Beijing Institute of Neurosurgery (CN)
- Weifang Chinese Medicine Hospital (CN)
Publication Details
- Journal
- Cancer Cell International
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1186/s12935-025-03700-6
- Citations
- 3
- Primary Topic
- Moyamoya disease diagnosis and treatment
- Type
- article
- Field-Weighted Citation Impact
- 5.00