The natural history of ductal carcinoma in situ: development, validation, and estimated outcomes of the SimDCIS model
SimDCIS provides strong accuracy across validation methods and is particularly sensitive to DCIS onset probability. Most DCIS will be found through screening, of which less than 50% of DCIS will be grade 3, less than 1 in 10 will regress, and 1 out of 5 DCIS will progress to IBC in biennial screening setting.
Authors
- Keris Poelhekken (ORCID: https://orcid.org/0000-0001-8884-1936)
- Bert van der Vegt (ORCID: https://orcid.org/0000-0002-2613-1506)
- Marcel J. W. Greuter (ORCID: https://orcid.org/0000-0001-5721-9159)
- Monique D. Dorrius (ORCID: https://orcid.org/0000-0001-9825-6001)
- Stephen William Duffy (ORCID: https://orcid.org/0000-0003-4901-7922)
- Geertruida H. de Bock (ORCID: https://orcid.org/0000-0003-3104-4471)
- Amanda Dibden (ORCID: https://orcid.org/0000-0002-0599-9840)
Institutions
- University Medical Center Groningen (NL)
- Queen Mary University of London (GB)
- University of Groningen (NL)
Publication Details
- Journal
- Breast Cancer Research and Treatment
- Published
- 2025-03-01
- DOI
- https://doi.org/10.1007/s10549-025-07639-0
- Citations
- 2
- Primary Topic
- Global Cancer Incidence and Screening
- Type
- article
- Field-Weighted Citation Impact
- 2.09