IL-1β and associated molecules as prognostic biomarkers linked with immune cell infiltration in colorectal cancer: an integrated statistical and machine learning approach
Overall, the elevated expression of IL-1β coupled with abnormal DNA methylation, and its consequent effect on the PI3K/Akt signaling pathway are relevant prognostic and therapeutic marker in CRC. Additional molecular candidates reveal insights into the epigenetic regulatory targets of CRC and their association with immune cell infiltration.
Authors
- Vino Sundararajan (ORCID: https://orcid.org/0000-0002-0015-8460)
- Karishma Sahoo
Institutions
- Vellore Institute of Technology University (IN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1007/s12672-025-01989-3
- Citations
- 8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 7.49