Lower immune senescence of T cell subsets among virologically suppressed Chinese men who have sex with men living with HIV in comparison with those ART naive

Virologically suppressed MSM living with HIV exhibit lower immune senescence of T cell subsets, which is more pronounced for CD8 cell subsets. The percentage of senescent naive T cells is significantly correlated with clinical immunity based on CD4 and CD8 T cell counts.

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Publication Details

Journal
BMC Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1186/s12879-025-10511-7
Citations
4
Primary Topic
Cytomegalovirus and herpesvirus research
Type
article
Field-Weighted Citation Impact
5.42
Controls
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article

Lower immune senescence of T cell subsets among virologically suppressed Chinese men who have sex with men living with HIV in comparison with those ART naive

Siyuan Yang, Huijun Li, Yunxia Tang, Fengting Yu et al.
4 citations
BMC Infectious Diseases
Cytomegalovirus and herpesvirus research
5.42
article

Lower immune senescence of T cell subsets among virologically suppressed Chinese men who have sex with men living with HIV in comparison with those ART naive

Siyuan Yang, Huijun Li, Yunxia Tang, Fengting Yu, Chengjie Ma, Li Li
article en
4 citations

Abstract

Virologically suppressed MSM living with HIV exhibit lower immune senescence of T cell subsets, which is more pronounced for CD8 cell subsets. The percentage of senescent naive T cells is significantly correlated with clinical immunity based on CD4 and CD8 T cell counts.

BMC Infectious DiseasesVol. 25(1)
Capital Medical University (CN), Beijing Ditan Hospital (CN)
Gender equality
Openalex Percentile: Top 5%
Cytomegalovirus and herpesvirus research
5.42
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