Prevalence and Antibiogram of Bacterial Pathogens Associated with Wounds in Patients Attending University of Harcourt Teaching Hospital

The study investigated the antibiogram profile of bacteria that were isolated from wounds of patients attending university of Port Harcourt Teaching Hospital, Port Harcourt.A total of 236 wound swab samples were collected from road traffic accident (RTA) (56), diabetic foot ulcer (40), post-surgical wound (38), burns (20), chronic leg ulcer (CLU) (20) and soft tissue infections (62) both from the in-patient and out-patient departments.These samples were processed, cultured and microbial isolates were identified following standard operating protocols in a diagnostic microbiology laboratory.The samples with bacterial growth were 208 (88%) of which 28 (12%) was poly microbial growth.The most common pathogen isolated was Staphylococcus aureus 64 (27%) followed by P. aeruginosa 42 (18%), Klebsiella pneumoniae 36 (15%), Proteus sp., 24 (10%), Escherichia coli 20 (8%), Streptococcus pyogenes 6 (3%) while 16 (7%) had mixed growth and 28 (12%) had no bacterial growth.Overall, 132 (56%) female subjects and 104 (44%) male subjects had bacterial growth.Soft tissue wounds 68(28.81%)was the most infected wound followed by surgical wound infection 56 (24%), diabetic foot ulcer 46 (19%), burns 22 (9%), CLU 22 (9%) and RTA 22 (9%).Sensitivity of ofloxacin to S. aureus, Pseudomonas aeruginosa, Klebsiella sp., Proteus sp., E. coli and S. pyogenes was 60 (94%), 40 (95%), 30 (83%), 22 (92%), 20 (100%) and 5 (83%) while ciprofloxacin was 60 (94%), 40 (95%), 36 (100 %), 24 (100%), 20 (100%) and 5 (83%) respectively.Pefloxacin sensitivity was 62 (97%), 42 (100%), 36 (100%), 24 (100%), 20 (100%) and 5 (83%) to S. aureus, P. aeruginosa, Klebsiella sp., Proteus sp., E. coli and S. pyogenes respectively.This study showed S. aureus and P. aeruginosa are the top pathogen isolated from wound infections. Prevalence and Antibiogram of Bacterial Pathogens Associated with Wounds in Patients Attending University of Harcourt Teaching Hospital Antibiogram of wound isolatesStaphylococcus aureus was sensitive to gentamicin, ofloxacin, ciprofloxacin, ceftriaxone, ceftazidime, cefuroxime, ampicillin, pefloxacin, erythromycin, streptomycin, septrin, nalidixic acid and ampiclox in 45 (70%), 60 (94%), 60 (94%), 14 (22%), 38 (59%), 21 (33%), 14 (22%), 62 (97%), 14 (22%), 21 (33%), 14 (22%), 14 (22%) and 21 (33%) respectively.Pseudomonas aeruginosa was sensitive to gentamicin, ofloxacin, ciprofloxacin, ceftriaxone, ceftazidime, pefloxacin, erythromycin, streptomycin, septrin and ampiclox in 15 (36%), 40 (95%), 40 (95%), 26 (62%), 18 (43%), 42 (100%), 26 (64%), 7 (17%), 26 (62%) and 7 (17%) respectively.Klebsiella sp. was sensitive to gentamicin, ofloxacin, ciprofloxacin, ceftriaxone, ceftazidime, cefuroxime, ampicillin, pefloxacin, erythromycin, streptomycin, septrin, nalidixic acid and amplicon in 12 (33%), 30 (83%), 36 (100%), 16 (44%), 20 (56%), 8 (22%), 4 (11%), 36 (100%), 16 (44%), 16 (44%), 16 (44%), 8 (22%) and 16 (44%) respectively.Proteus sp. was sensitive to gentamicin, ofloxacin, ciprofloxacin, ceftriaxone, erythromycin, streptomycin, septrin and ampiclox in 20 (83%), 22 (92%), 24 (100%), 14 (71%), 11