Transcriptomic profile of RNA pseudouridine modification as a biomarker for cellular senescence associated with survival outcomes in colorectal cancer
Overall, these findings reveal that RNA Ψ modification connected aging and cancer and provided novel insights into biomarker-guided cancer regimens.
Authors
- Yuanhui Wu (ORCID: https://orcid.org/0000-0002-7004-1663)
- Yingguo Gan
- Ji Cui (ORCID: https://orcid.org/0000-0001-8905-8513)
- Ze Yuan (ORCID: https://orcid.org/0009-0006-6691-0818)
- Haotian Liu (ORCID: https://orcid.org/0009-0004-5061-3873)
- Meijin Huang (ORCID: https://orcid.org/0000-0002-5483-4591)
- Jingrong Weng (ORCID: https://orcid.org/0000-0002-1665-1559)
- Yanxin Luo (ORCID: https://orcid.org/0000-0002-5200-3997)
- Mingzhe Huang (ORCID: https://orcid.org/0000-0002-8103-9382)
- Huichuan Yu (ORCID: https://orcid.org/0000-0001-8357-1615)
- Zhenghua Chen (ORCID: https://orcid.org/0000-0002-1719-0328)
- Xuan Li (ORCID: https://orcid.org/0009-0004-1337-3049)
- Jinxin Lin (ORCID: https://orcid.org/0009-0003-0543-6743)
- Zixiao Wan
- Ziming Li (ORCID: https://orcid.org/0009-0005-5718-2145)
- Junyi Han (ORCID: https://orcid.org/0000-0002-5035-2376)
- Kaixin Lin
- Tuoyang Li
Institutions
- Sun Yat-sen University (CN)
- Sixth Affiliated Hospital of Sun Yat-sen University (CN)
- The First Affiliated Hospital, Sun Yat-sen University (CN)
Publication Details
- Journal
- BMC Biology
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12915-025-02170-6
- Citations
- 2
- Primary Topic
- RNA modifications and cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.61