Inferring protein from transcript abundances using convolutional neural networks

For H. sapiens, our model improves prediction performance by nearly 50% compared to previous sequence-based approaches, and for A. thaliana it represents the first model of its kind. The model's learned motifs recapitulate known regulatory elements, supporting its utility in systems-level and hypothesis-driven research approaches related to protein regulation.

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Publication Details

Journal
BioData Mining
Published
2025-02-27
DOI
https://doi.org/10.1186/s13040-025-00434-z
Citations
4
Primary Topic
Advanced Proteomics Techniques and Applications
Type
article
Field-Weighted Citation Impact
3.03

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article

Inferring protein from transcript abundances using convolutional neural networks

Patrick Schwehn, Pascal Falter‐Braun
4 citations
BioData Mining
Advanced Proteomics Techniques and Applications
3.03
article

Inferring protein from transcript abundances using convolutional neural networks

Patrick Schwehn, Pascal Falter‐Braun
article en
4 citations

Abstract

For H. sapiens, our model improves prediction performance by nearly 50% compared to previous sequence-based approaches, and for A. thaliana it represents the first model of its kind. The model's learned motifs recapitulate known regulatory elements, supporting its utility in systems-level and hypothesis-driven research approaches related to protein regulation.

BioData MiningVol. 18(1)
Target (Germany) (DE)
Bundesministerium für Bildung und Forschung, Horizon 2020 Framework Programme
Openalex Percentile: Top 10%
Advanced Proteomics Techniques and Applications
3.03
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