BIN1 inhibited tumor growth, metastasis and stemness by ALDH1/NOTCH pathway in bladder carcinoma
Our findings demonstrate that BIN1 functions as a tumor suppressor in BLCA and suggest its potential utility as both a diagnostic biomarker and therapeutic target for BLCA treatment.
Authors
- Jirong Wang (ORCID: https://orcid.org/0000-0003-1136-0928)
- Tuanjie Che (ORCID: https://orcid.org/0009-0002-6314-6683)
- Shengjun Fu (ORCID: https://orcid.org/0009-0001-8619-8964)
- Shun Wan
- Liyun Ding (ORCID: https://orcid.org/0000-0002-1625-6145)
- Ya-long Zhang
- Xiaojun Fan (ORCID: https://orcid.org/0000-0003-1256-5343)
- Siyu Chen (ORCID: https://orcid.org/0000-0003-1156-7910)
- Yang Li (ORCID: https://orcid.org/0000-0001-9612-2704)
- Chenyang Wang
- Hao Wang (ORCID: https://orcid.org/0009-0001-6529-6282)
- Jinlong Cao
- Jianwei Yang
- Kunpeng Li (ORCID: https://orcid.org/0000-0002-2269-0458)
- Xiaoran Li (ORCID: https://orcid.org/0000-0002-5910-8054)
Institutions
- Lanzhou University Second Hospital (CN)
- Annoroad Gene Technology (China) (CN)
- Gansu Provincial Center for Disease Control and Prevention (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Hereditas
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s41065-025-00384-w
- Citations
- 2
- Primary Topic
- Bladder and Urothelial Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 4.01
Funders
- National Natural Science Foundation of China