Altered functional connectivity and hyperactivity of the caudal hippocampus in schizophrenia compared with bipolar disorder: a resting state fMRI (functional magnetic resonance imaging) study
These findings confirm an important contribution of hippocampal dysfunction, especially of the cHipp, in schizophrenia. Further, hyper-connectivity and hyperactivity of the cHipp could serve as a biomarker for therapeutic development.
Authors
- Gong‐Jun Ji (ORCID: https://orcid.org/0000-0002-7073-5534)
- Yanghua Tian (ORCID: https://orcid.org/0000-0001-5038-0599)
- Kai Wang (ORCID: https://orcid.org/0000-0002-6197-914X)
- Zhiyong Li (ORCID: https://orcid.org/0000-0002-6814-9165)
- Wenli Wang (ORCID: https://orcid.org/0000-0002-7095-7807)
- Yuan Ruan
- Li Zhang (ORCID: https://orcid.org/0000-0002-4456-8787)
- Le Sun
Institutions
- Anhui Medical University (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Anhui Mental Health Center (CN)
Publication Details
- Journal
- BMC Psychiatry
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12888-025-06632-7
- Citations
- 2
- Primary Topic
- Functional Brain Connectivity Studies
- Type
- article
- Field-Weighted Citation Impact
- 2.86
Funders
- National Natural Science Foundation of China