ZEB1 expression in Th17 cells correlated with p-STAT3 in human apical periodontitis
The expression of ZEB1 was significantly elevated in PGs and RCs, and correlated with Th17 cells and p-STAT3 expression. This study revealed that ZEB1 is a potential player correlated with STAT3 activation and Th17 cells in apical periodontitis pathogenesis.
Authors
- Xiaoyue Sun (ORCID: https://orcid.org/0000-0002-9793-2116)
- Mingwen Liu
- Lingxin Zhu (ORCID: https://orcid.org/0000-0002-6762-7882)
- Li Wang (ORCID: https://orcid.org/0000-0001-8981-1472)
- Wei Zhang (ORCID: https://orcid.org/0000-0001-7588-7249)
- Zijun Wang (ORCID: https://orcid.org/0000-0002-2095-2151)
- Jingwen Yang (ORCID: https://orcid.org/0000-0002-8206-2584)
- Qian Yang (ORCID: https://orcid.org/0000-0002-6111-8411)
- Qing Nie (ORCID: https://orcid.org/0009-0007-6876-9843)
Institutions
- Wuhan University (CN)
Publication Details
- Journal
- BMC Oral Health
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12903-025-05633-y
- Primary Topic
- Immune Response and Inflammation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Natural Science Foundation of Hubei Province
- Fundamental Research Funds for the Central Universities