Refining Unfavorable Vaginal Microbial Community in Infertile Women Subjected to Precision Probiotic Intervention: An Exploratory Single-Arm, Prospective, Open-Label, Interventional Study
Although CST-III and CST-IV are generally considered detrimental, gynecologists should not refrain from performing IVF in these women if they have been previously subjected to a consortium of precision probiotics treatments, as the administration of specific probiotics reduces the presence of pathogenic bacteria promoting the increase in lactobacilli associated with a healthy vaginal ecosystem, which could impact pregnancy success.
Authors
- Lodovico Parmegiani (ORCID: https://orcid.org/0000-0003-3901-885X)
- Franca Marino (ORCID: https://orcid.org/0000-0003-1837-7810)
- Giovanna Cocomazzi (ORCID: https://orcid.org/0000-0003-2831-934X)
- Edy Virgili
- Walter Ciampaglia (ORCID: https://orcid.org/0000-0001-9367-866X)
- Matteo Cerboneschi (ORCID: https://orcid.org/0000-0002-6448-2622)
- Viviana Contu
- Giorgio Maria Baldini (ORCID: https://orcid.org/0000-0002-5061-8007)
- Lino Del Pup (ORCID: https://orcid.org/0000-0003-2979-3844)
- Matteo Buccheri
- Valerio Pazienza (ORCID: https://orcid.org/0000-0002-3492-1153)
- Christine Allen (ORCID: https://orcid.org/0000-0002-4916-3965)
- Simone Palini (ORCID: https://orcid.org/0000-0002-2445-6518)
- Domenico Baldini (ORCID: https://orcid.org/0000-0003-1433-504X)
- Daniele De Ruvo
- Silvia De Stefani
- Monica Antinori
Institutions
- Università di Camerino (IT)
- Santa Maria Nuova Hospital (IT)
- Casa Sollievo della Sofferenza (IT)
- Ospedale Cervesi di Cattolica (IT)
- Ospedale Humanitas Gradenigo (IT)
- GynePro Medical (IT)
Publication Details
- Journal
- Microorganisms
- Published
- 2025-02-28
- DOI
- https://doi.org/10.3390/microorganisms13030547
- Citations
- 5
- Primary Topic
- Reproductive tract infections research
- Type
- article
- Field-Weighted Citation Impact
- 5.92