Bioinformatics analysis of shared biomarkers and immune pathways of preeclampsia and periodontitis
Shared hub genes and immunologic pathways were identified in PE and PD, characterised by crosstalk between BIN2, LYN, NEDD9, and PIK3AP1, suggesting the pathogenesis of PE and PD, which could pave the way for the development of effective diagnostic, treatment, and management strategies.
Authors
- Yadan Liu
- Ying Xiang (ORCID: https://orcid.org/0000-0001-6727-9999)
- Jinghui Xu
- Huanqiang Zhao (ORCID: https://orcid.org/0000-0002-3664-8031)
- Ping Wen (ORCID: https://orcid.org/0000-0001-6042-9974)
- Yinan Wang (ORCID: https://orcid.org/0000-0001-8714-2105)
- Xiaotian Li (ORCID: https://orcid.org/0000-0002-2051-4581)
- He-Feng Huang
- Yaping Zhu
- Qiongjie Zhou
- Fangyi Ruan
Institutions
- Shanghai Jiao Tong University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Shenzhen Maternity and Child Healthcare Hospital (CN)
- International Peace Maternity & Child Health Hospital (CN)
- Women's Hospital, School of Medicine, Zhejiang University (CN)
- Obstetrics and Gynecology Hospital of Fudan University (CN)
- Southern Medical University (CN)
- Zhejiang University (CN)
Publication Details
- Journal
- BMC Pregnancy and Childbirth
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12884-025-07277-w
- Citations
- 4
- Primary Topic
- Biomarkers in Disease Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 3.19
Funders
- National Natural Science Foundation of China
- Sanming Project of Medicine in Shenzhen
- National Key Research and Development Program of China