Activation of Nrf2 pathway by 4-Octyl itaconate enhances donor lung function in cold preservation settings
Incorporating 4-OI into cold preservation solutions appears promising for alleviating CI/R-induced bronchial epithelial injury and enhancing lung transplant outcomes via Nrf2 pathway activation.
Authors
- Xinliang Gao (ORCID: https://orcid.org/0000-0003-0767-2267)
- Mingbo Tang (ORCID: https://orcid.org/0000-0001-5097-0644)
- Jianzun Ma
- Wei Liu (ORCID: https://orcid.org/0000-0003-4987-4246)
- Jialin Li (ORCID: https://orcid.org/0000-0003-4972-3480)
- Zhengrui Liu
Institutions
- Jilin University (CN)
- First Hospital of Jilin University (CN)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12931-025-03151-7
- Citations
- 4
- Primary Topic
- Transplantation: Methods and Outcomes
- Type
- article
- Field-Weighted Citation Impact
- 8.03