Past use of metformin is associated with increased risk of myelodysplastic syndrome development in diabetes mellitus patients: a cross-sectional study of 54,869 patients

Previous exposure to metformin amongst DM patients is associated with an increased risk for MDS development later in life. This is a preliminary, cross-sectional study that show that larger studies in variable MDS patient populations are warranted.

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Journal
BMC Pharmacology and Toxicology
Published
2025-02-27
DOI
https://doi.org/10.1186/s40360-025-00882-7
Primary Topic
Metabolism, Diabetes, and Cancer
Type
article
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article

Past use of metformin is associated with increased risk of myelodysplastic syndrome development in diabetes mellitus patients: a cross-sectional study of 54,869 patients

Tamer Hellou, Reut Kassif Lerner, Gad Segal, Ahlam Athamna et al.
BMC Pharmacology and Toxicology
Metabolism, Diabetes, and Cancer
article

Past use of metformin is associated with increased risk of myelodysplastic syndrome development in diabetes mellitus patients: a cross-sectional study of 54,869 patients

Tamer Hellou, Reut Kassif Lerner, Gad Segal, Ahlam Athamna, Aviv Philip Goncharov, Shir Portugez, Guy Dumanis, Aya Berman, A. Stern, Ekram Nimer, Eden Trodler, Imanuel Carlebach, Omer Kahlon, Maysan Abu Jwella
article en

Abstract

Previous exposure to metformin amongst DM patients is associated with an increased risk for MDS development later in life. This is a preliminary, cross-sectional study that show that larger studies in variable MDS patient populations are warranted.

BMC Pharmacology and ToxicologyVol. 26(1)
Tel Aviv University (IL), Medical University of Silesia (PL), Sheba Medical Center (IL), Geha Mental Health Center (IL), Ariel University (IL), Palacký University Olomouc (CZ), Kharkiv National Medical University (UA)
Good health and well-being
Openalex Percentile: Top 97%
Metabolism, Diabetes, and Cancer
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