A novel stemness-related lncRNA signature predicts prognosis, immune infiltration and drug sensitivity of clear cell renal cell carcinoma
We uncovered the crucial associations between SRlncRNAs and the prognosis of ccRCC. By leveraging these findings, we developed a novel SRlncRNA-related signature and a user-friendly web calculator. This signature holds great potential in facilitating risk stratification and guiding tailored treatment strategies for ccRCC patients. Both in vitro and in vivo experiments confirmed the role of SRlncRNAs in the progression of ccRCC.
Authors
- Jinchao Ma (ORCID: https://orcid.org/0000-0002-5995-0137)
- Yao Lin (ORCID: https://orcid.org/0000-0002-0493-0155)
- Peng Du
- Yong Yang (ORCID: https://orcid.org/0000-0001-5701-046X)
- Ruijian You
- Ziyi Yu
- Jia Liu (ORCID: https://orcid.org/0000-0002-9771-192X)
Institutions
- Peking University (CN)
- Peking University Cancer Hospital (CN)
- Peking University First Hospital (CN)
- Ministry of Education (ET)
Publication Details
- Journal
- Journal of Translational Medicine
- Published
- 2025-02-27
- DOI
- https://doi.org/10.1186/s12967-025-06251-6
- Citations
- 8
- Primary Topic
- Cancer-related molecular mechanisms research
- Type
- article
- Field-Weighted Citation Impact
- 7.49