Correlation between radiation dose to bone marrow subregions and acute hematologic toxicity inendometrial cancer treated with external beam radiotherapy
In this experience a dose constraint age-dependent was proposed, to reduce the risk of HT.The volume of lombo-sacral pelvis receiving low-dose radiation (V20 LSBM > 64 %) seems to be associated with HT in younger patients; instead in older than 70 patients the percentage of V20Gy LSBM seems not correlate with risk of toxicity. Future investigations should seek to confirm these findings through the inclusion of these parameters in the planning process.
Authors
- Valentina Lancellotta (ORCID: https://orcid.org/0000-0003-3507-7051)
- Viola De Luca (ORCID: https://orcid.org/0000-0002-9914-0075)
- Gabriella Ferrandina (ORCID: https://orcid.org/0000-0003-4672-4197)
- Davide Cusumano (ORCID: https://orcid.org/0000-0001-8626-0003)
- M.A. Gambacorta
- R. Autorino
- Raffaella Michela Rinaldi (ORCID: https://orcid.org/0009-0009-5133-8507)
- Maura Campitelli (ORCID: https://orcid.org/0000-0003-1210-5232)
- R. Giannini
- Gabriella Macchia (ORCID: https://orcid.org/0000-0002-0529-201X)
- Silvia Di Franco (ORCID: https://orcid.org/0009-0007-0001-3935)
Institutions
- University of Molise (IT)
- Agostino Gemelli University Polyclinic (IT)
- Ospedale Madonna Delle Grazie (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
Publication Details
- Journal
- Clinical and Translational Radiation Oncology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.ctro.2025.100942
- Citations
- 1
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.06