A rare presentation of bilateral synchronous renal tumours misdiagnosed as tuberculosis

A 32-year-old woman with dialysis-requiring kidney failure presented with constitutional symptoms and bilateral kidney masses and was initially diagnosed with renal tuberculosis (TB). However, despite TB treatment, her condition deteriorated, leading to a right nephrectomy. Histopathological examination revealed the presence of embryonal rhabdomyosarcoma (ERMS), a rare malignancy typically seen in paediatric populations. Alternative diagnoses, even rare ones like ERMS, should be considered when dealing with bilateral kidney masses. Radical nephrectomy remains the primary treatment for ERMS, but adjuvant therapies may also be beneficial. Contribution: This case highlights the diagnostic challenges of bilateral kidney masses and the importance of considering rare malignancies in the differential diagnosis. Prompt histopathological evaluation is crucial for accurate diagnosis and timely management.

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Publication Details

Journal
South African Journal of Oncology
Published
2025-02-28
DOI
https://doi.org/10.4102/sajo.v9i0.311
Primary Topic
Renal cell carcinoma treatment
Type
article
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article

A rare presentation of bilateral synchronous renal tumours misdiagnosed as tuberculosis

Feziwe Busiswa Bisiwe, Debi M. Moagi
South African Journal of Oncology
Renal cell carcinoma treatment
article

A rare presentation of bilateral synchronous renal tumours misdiagnosed as tuberculosis

Feziwe Busiswa Bisiwe, Debi M. Moagi
article en

Abstract

A 32-year-old woman with dialysis-requiring kidney failure presented with constitutional symptoms and bilateral kidney masses and was initially diagnosed with renal tuberculosis (TB). However, despite TB treatment, her condition deteriorated, leading to a right nephrectomy. Histopathological examination revealed the presence of embryonal rhabdomyosarcoma (ERMS), a rare malignancy typically seen in paediatric populations. Alternative diagnoses, even rare ones like ERMS, should be considered when dealing with bilateral kidney masses. Radical nephrectomy remains the primary treatment for ERMS, but adjuvant therapies may also be beneficial. Contribution: This case highlights the diagnostic challenges of bilateral kidney masses and the importance of considering rare malignancies in the differential diagnosis. Prompt histopathological evaluation is crucial for accurate diagnosis and timely management.

South African Journal of OncologyVol. 9
University of the Free State (ZA)
Openalex Percentile: Top 94%
Renal cell carcinoma treatment
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