Neuraxial Analgesia and Anesthesia for Labor and Cesarean Delivery in a Patient with Juvenile Huntington Disease: A Case Report

The rarity of Huntington's disease (HD) parturients implies that anesthesiologists have little exposure to the management of these patients. We explore techniques for the management of a 21-year-old parturient with symptomatic HD who underwent successful neuraxial anesthesia for labor and subsequent cesarean delivery. We provide guidance on perioperative medications for comorbidities associated with HD. Dexmedetomidine, which we administered neuraxially, appears to have significant potential for the perioperative diminution of choreiform movements. Current anesthetic management of HD cannot be informed by traditional research methodology and therefore much information must be gleaned from the limited available case reports.

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Journal
A&A Practice
Published
2025-02-28
DOI
https://doi.org/10.1213/xaa.0000000000001926
Primary Topic
Genetic Neurodegenerative Diseases
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article
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article

Neuraxial Analgesia and Anesthesia for Labor and Cesarean Delivery in a Patient with Juvenile Huntington Disease: A Case Report

Leonard J. Soloniuk, Ioana Pasca, Jonathan Spencer Jones, Mira Bishawi et al.
4 links
A&A Practice
Genetic Neurodegenerative Diseases
article

Neuraxial Analgesia and Anesthesia for Labor and Cesarean Delivery in a Patient with Juvenile Huntington Disease: A Case Report

Leonard J. Soloniuk, Ioana Pasca, Jonathan Spencer Jones, Mira Bishawi, Ashish Sinha, Christopher J. Baker
article en

Abstract

The rarity of Huntington's disease (HD) parturients implies that anesthesiologists have little exposure to the management of these patients. We explore techniques for the management of a 21-year-old parturient with symptomatic HD who underwent successful neuraxial anesthesia for labor and subsequent cesarean delivery. We provide guidance on perioperative medications for comorbidities associated with HD. Dexmedetomidine, which we administered neuraxially, appears to have significant potential for the perioperative diminution of choreiform movements. Current anesthetic management of HD cannot be informed by traditional research methodology and therefore much information must be gleaned from the limited available case reports.

A&A PracticeVol. 19(3)
University of California, Riverside (US), Loma Linda University (US), Riverside University Health System - Medical Center (US), University of California San Diego (US)
Decent work and economic growth
Openalex Percentile: Top 95%
Genetic Neurodegenerative Diseases
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Neuraxial Analgesia and Anesthesia for Labor and Cesarean Delivery in a Patient with Juvenile Huntington Disease: A Case Report — Leonard J. Soloniuk, Ioana Pasca, et al. · A&A Practice (2025) | TGRS Research Map | TGRS