Beyond glycemic control: semaglutide's multifaceted impact on metabolic health

Achieving ideal glycemic control is essential for those with Type 2 Diabetes Mellitus (T2DM), as is avoiding hypoglycemia, controlling body weight, and lowering cardiovascular risk. A prospective treatment strategy that meets these demands is provided by agonists of the Glucagon-Like Peptide-1 receptor. These drugs block glucagon secretion, slow stomach emptying, decrease appetite, and increase glucose-dependent insulin secretion, all of which help control weight and minimize the risk of hypoglycemic episodes. Furthermore, a number of GLP-1 receptor agonists have shown promising increase in renal and cardiovascular health. Patients might have a more convenient treatment regimen because they are accessible as weekly or daily injections. Furthermore, a lower risk of cardiovascular disease has been associated with some GLP-1 receptor agonists. According to recent studies, these substances may also have a number of neuroprotective advantages, such as increasing neurogenesis, lowering cell death, shielding neurons from oxidative stress, and lowering neuroinflammation in a range of neurological disorders. These substances are therefore being investigated as potential therapies for neurodegenerative illnesses like Parkinson's and Alzheimer's.

Authors

Publication Details

Journal
International Journal of Science and Research Archive
Published
2025-02-28
DOI
https://doi.org/10.30574/ijsra.2025.14.2.0503
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Beyond glycemic control: semaglutide's multifaceted impact on metabolic health

Shaik Parveen, Ajay Boddu, Sharanya Narala
International Journal of Science and Research Archive
Diabetes Treatment and Management
article

Beyond glycemic control: semaglutide's multifaceted impact on metabolic health

Shaik Parveen, Ajay Boddu, Sharanya Narala
article en

Abstract

Achieving ideal glycemic control is essential for those with Type 2 Diabetes Mellitus (T2DM), as is avoiding hypoglycemia, controlling body weight, and lowering cardiovascular risk. A prospective treatment strategy that meets these demands is provided by agonists of the Glucagon-Like Peptide-1 receptor. These drugs block glucagon secretion, slow stomach emptying, decrease appetite, and increase glucose-dependent insulin secretion, all of which help control weight and minimize the risk of hypoglycemic episodes. Furthermore, a number of GLP-1 receptor agonists have shown promising increase in renal and cardiovascular health. Patients might have a more convenient treatment regimen because they are accessible as weekly or daily injections. Furthermore, a lower risk of cardiovascular disease has been associated with some GLP-1 receptor agonists. According to recent studies, these substances may also have a number of neuroprotective advantages, such as increasing neurogenesis, lowering cell death, shielding neurons from oxidative stress, and lowering neuroinflammation in a range of neurological disorders. These substances are therefore being investigated as potential therapies for neurodegenerative illnesses like Parkinson's and Alzheimer's.

International Journal of Science and Research ArchiveVol. 14(2)
Openalex Percentile: Top 95%
Diabetes Treatment and Management
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.

Beyond glycemic control: semaglutide's multifaceted impact on metabolic health — Shaik Parveen, Ajay Boddu, et al. · International Journal of Science and Research Archive (2025) | TGRS Research Map | TGRS