Preparation of diltiazem HCl-modified release formulation using cation-exchange resin as a single excipient
This study successfully demonstrates that Dowex® 50WX8 (Na<sup>+</sup> form) can be used as a single excipient in diltiazem formulations, providing both chemical stability and sustained release without requiring additional polymer coatings.
Authors
- Khouloud A. Alkhamis (ORCID: https://orcid.org/0000-0002-8222-9209)
- Suhair S. Al‐Nimry (ORCID: https://orcid.org/0000-0002-7164-0158)
Institutions
- Jordan University of Science and Technology (JO)
Publication Details
- Journal
- Pharmaceutical Development and Technology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1080/10837450.2025.2474092
- Citations
- 2
- Primary Topic
- Protein purification and stability
- Type
- article
- Field-Weighted Citation Impact
- 1.61