Impact of Marasmic Malnutrition on Visceral Leishmaniasis: Progression and Treatment Efficacy in a Murine Model
Our data suggested that marasmic malnutrition affects the establishment and progression of <i>Leishmania</i> infection, in addition to reducing the efficacy of standard treatment. Furthermore, the refeeding intervention used did not fully reverse the observed effects. These findings highlight the potential importance of nutritional interventions in the clinical management of visceral leishmaniasis in malnourished populations.
Authors
- Taiana Ferreira-Paes (ORCID: https://orcid.org/0000-0002-8953-3537)
- Paula Seixas-Costa
- Elmo E. Almeida-Amaral (ORCID: https://orcid.org/0000-0003-1363-3176)
- Paula Mello De Luca (ORCID: https://orcid.org/0000-0002-2017-8602)
- Luiza F. O. Gervazoni (ORCID: https://orcid.org/0000-0003-2694-8249)
Institutions
- Fundação Oswaldo Cruz (BR)
Publication Details
- Journal
- Nutrients
- Published
- 2025-02-28
- DOI
- https://doi.org/10.3390/nu17050849
- Primary Topic
- Research on Leishmaniasis Studies
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
- Conselho Nacional de Desenvolvimento Científico e Tecnológico
- Fundação Carlos Chagas Filho de Amparo à Pesquisa do Estado do Rio de Janeiro