Prenatal inflammation exacerbates hyperoxia-induced neonatal brain injury
Prenatal inflammation combined with postnatal hyperoxia results in aggravated myelination deficits and inflammatory responses compared to single insults, making it an ideal model to improve our understanding of the complex pathophysiology underlying WMI and to evaluate urgently needed therapies.
Authors
- Ralf Herrmann
- Karina Kempe
- Meray Serdar (ORCID: https://orcid.org/0000-0001-7838-9413)
- Josephine Herz (ORCID: https://orcid.org/0000-0001-8132-7459)
- Stefanie Obst (ORCID: https://orcid.org/0000-0002-9797-1262)
- Ursula Felderhoff‐Müser (ORCID: https://orcid.org/0000-0002-7765-8893)
- Nicole Labusek (ORCID: https://orcid.org/0000-0002-1978-6176)
- Ivo Bendix (ORCID: https://orcid.org/0000-0002-9751-3640)
- Markus Gallert
- K. Walther
Institutions
- University of Duisburg-Essen (DE)
Publication Details
- Journal
- Journal of Neuroinflammation
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12974-025-03389-4
- Citations
- 7
- Primary Topic
- Neonatal and fetal brain pathology
- Type
- article
- Field-Weighted Citation Impact
- 24.46
Funders
- Universitätsklinikum Essen