The OPTIMUS International Consensus Guidance for Monitoring User-Reported Outcomes of Opioid Maintenance Treatment: a Delphi Study

Opioid use disorder is a major cause of drug-related harm and mortality. These can be reduced by expanded access to evidence-based and highly effective opioid agonist maintenance treatment or therapy (OMT). There is a lack of consensus on how to assess opioid use disorder treatment outcomes, and key health outcomes are often omitted. We report the results of a Delphi study to produce service user- and public health–centred international consensus guidance for OMT outcomes monitoring. An international group of 110 substance use specialists in 32 countries, including service providers, researchers and people with lived experience of OMT, produced draft guidance over multiple meetings. The guidance includes a service user-reported OMT outcomes questionnaire, based on 26 core questions, plus optional questions, in six domains (treatment, physical health, mental health, social functioning, substance use, quality of life). A Delphi panel of 757 OMT professionals and service users (46%) from 29 countries, of which 40% were female, reviewed the questionnaire over two survey rounds, supporting and improving it (round 2 mean agreement score on a 1-6 Likert scale: 5.2; 95%CI 5.1–5.3). By focusing on service user–reported and public health–centred outcomes of OMT, the OPTIMUS consensus guidance aims to facilitate the communication between service providers and service users and improve the quality of care and the survival, health and quality of life of OMT service users.

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Publication Details

Journal
International Journal of Mental Health and Addiction
Published
2025-02-28
DOI
https://doi.org/10.1007/s11469-024-01426-6
Citations
1
Primary Topic
Opioid Use Disorder Treatment
Type
article
Field-Weighted Citation Impact
1.88
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article

The OPTIMUS International Consensus Guidance for Monitoring User-Reported Outcomes of Opioid Maintenance Treatment: a Delphi Study

Dimos Fotopoulos, Perrine Roux, Luis Sordo, Laura M. Dale et al.
1 citations
International Journal of Mental Health and Addiction
Opioid Use Disorder Treatment
1.88
article

The OPTIMUS International Consensus Guidance for Monitoring User-Reported Outcomes of Opioid Maintenance Treatment: a Delphi Study

Dimos Fotopoulos, Perrine Roux, Luis Sordo, Laura M. Dale, Gabriela Barbaglia, Peter Blanken, Ioanna Yiasemi, Evi Kyprianou, Markus Partanen, Viktor Mravčík, Hanna Putkonen, Jana Darejan Javakhishvili, Tanja Schwarz, Thomas F. Martinelli, Mariam Razmadze, Claudia Bernardini, Emilis Subata, Tim Millar, Marta Torrens, Kirsten Marchand, Sonila Bitri, Liljana Ignjatova, Zuzana Kamendy, Alexander Yale Walley, Mads Uffe Pedersen, Lucas Wiessing, Daniel Dacosta‐Sánchez, Catherine Comiskey, A Kiss, Barbara Janíková, Bernd Schulte, Jérôme Antoine, Máté Kapitány‐Fövény, Geert Dom, Vendula Běláčková, Britta Jacobsen, Siniša Skočibušić, Lisa Strada, Patrizia Carrieri, Esmeralda Thoma, Kenneth I. E. Macleod, Paulo Seabra, Venus Athena Vangsgaard Fabricius, Hugo Faria, Nemanja Inić, Prakashini Banka-Cullen, Naser J. Y. Mustafa, Saed A. S. Belbaisi, Diāna Vanaga‐Arāja, Maria João Silva, Deniz Akartuna, Gabriele Fischer, Saša Čelojević, Lina Hijazi, Dario Ičanović, Haris Jakavicius, Roksana Karczewska, Andreas Krasias, Dominique Lamy, Inga Landsmane, Bojan Nikolovski, Filippo Maria Pericoli, Olena Puhach, Rebecca Reifenstein, Dana Špringelová, Beata Stelmaszczyk, Kateryna Terykh, Piotr Tubelewicz
article en
1 citations

Abstract

Opioid use disorder is a major cause of drug-related harm and mortality. These can be reduced by expanded access to evidence-based and highly effective opioid agonist maintenance treatment or therapy (OMT). There is a lack of consensus on how to assess opioid use disorder treatment outcomes, and key health outcomes are often omitted. We report the results of a Delphi study to produce service user- and public health–centred international consensus guidance for OMT outcomes monitoring. An international group of 110 substance use specialists in 32 countries, including service providers, researchers and people with lived experience of OMT, produced draft guidance over multiple meetings. The guidance includes a service user-reported OMT outcomes questionnaire, based on 26 core questions, plus optional questions, in six domains (treatment, physical health, mental health, social functioning, substance use, quality of life). A Delphi panel of 757 OMT professionals and service users (46%) from 29 countries, of which 40% were female, reviewed the questionnaire over two survey rounds, supporting and improving it (round 2 mean agreement score on a 1-6 Likert scale: 5.2; 95%CI 5.1–5.3). By focusing on service user–reported and public health–centred outcomes of OMT, the OPTIMUS consensus guidance aims to facilitate the communication between service providers and service users and improve the quality of care and the survival, health and quality of life of OMT service users.

International Journal of Mental Health and Addiction
University College Dublin (IE), Semmelweis University (HU), Scottish Power (United Kingdom) (GB), Universidad Complutense de Madrid (ES), University of Medicine Tirana (AL), Boston Medical Center (US), European Medicines Agency (NL), Providence Health Care (CA), University of Mons (BE), University of Antwerp (BE), University of Mostar (BA), Inserm (FR), Universität Hamburg (DE), Universitat Pompeu Fabra (ES), Vilnius University (LT), Ilia State University (GE), Riga Technical University (LV), Aarhus University (DK), Trinity College Dublin (IE), Charles University (CZ), University Clinical Hospital Mostar (BA), Mother Teresa Hospital (AL), Mental Health Services (DK), University of Manchester (GB), Hospital Clínico San Carlos (ES), Escola Superior de Saúde Egas Moniz (PT), UNSW Sydney (AU), University of Cyprus (CY), Pan-European University (SK), Finnish Institute for Health and Welfare (FI), Parnassia Groep (NL), Institute for Plant Protection and Environment (RS), Center for Physical Sciences and Technology (LT), Government of Ukraine (UA), Addiction Switzerland (CH), Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES), Limassol General Hospital (CY), National Institute of Menthal Health, Neurology and Neurosurgery - Nyírő Gyula Hospital (HU), Center for Health, Exercise and Sport Sciences (RS), Hospital de Egas Moniz (PT), University Medical Center Hamburg-Eppendorf (DE), National Drug Addiction Center (BG), Escola Superior de Enfermagem da Universidade de Lisboa (PT), Centre Hospitalier Philippe Pinel (FR), Orszagos Kornyezetegeszsegugyi Intezet (HU), Trimbos Institute (NL), Cancer Clinic (US), Gesundheit Österreich (AT), St Anna Children's Hospital (AT), Osakidetza (ES), Institute of Neurology, Psychiatry and Narcology (UA), Polish Agency for Enterprise Development (PL), Centre for Advancing Health Outcomes (CA), Taiwan Centers for Disease Control (TW), State Institute for Drug Control (SK), PHI University Psychiatric Clinic - Skopje (MK), Sciensano (Belgium) (BE), Klinik und Poliklinik für Psychiatrie und Psychotherapie (DE), Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública (ES), Společnost pro Obnovu Vesnice a Malého Města (CZ), Institut Scientifique de Santé Publique (BE), Economic & Social Sciences, Health Systems & Medical Informatics (FR), Agencia de Salud Pública de Barcelona (ES), Direção Geral do Património Cultural (PT), Institut de Recherche pour le Développement (FR), Medical University of Vienna (AT), Ss. Cyril and Methodius University in Skopje (MK), Universidad de Huelva (ES), University of Latvia (LV)
Openalex Percentile: Top 18%
Opioid Use Disorder Treatment
1.88
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