Epidemiology of myocardial injury in trauma patients: proposed phenotypes for future research

Troponin elevation occurs in 7% of all trauma admissions and it identifies the seriously injured high-risk cohort. The timing of the maximum Troponin concentration seems to describe three distinct phenotypes. "Hyperacute" with most favourable outcomes, "Subacute" with severe trauma and tissue injury requiring major resource utilisation and associated with the highest mortality rate, and "Late" characterised by ECG and ECHO changes suggesting primary ischaemic cardiac pathology.

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Publication Details

Journal
European Journal of Trauma and Emergency Surgery
Published
2025-02-28
DOI
https://doi.org/10.1007/s00068-025-02798-7
Citations
1
Primary Topic
Cardiac Arrest and Resuscitation
Type
article
Field-Weighted Citation Impact
2.25

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Epidemiology of myocardial injury in trauma patients: proposed phenotypes for future research

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article

Epidemiology of myocardial injury in trauma patients: proposed phenotypes for future research

Zsolt J. Balogh, Simone Meakes, Natasha Weaver, Jett Karolewski, J Williams, Karen Gane
article en
1 citations

Abstract

Troponin elevation occurs in 7% of all trauma admissions and it identifies the seriously injured high-risk cohort. The timing of the maximum Troponin concentration seems to describe three distinct phenotypes. "Hyperacute" with most favourable outcomes, "Subacute" with severe trauma and tissue injury requiring major resource utilisation and associated with the highest mortality rate, and "Late" characterised by ECG and ECHO changes suggesting primary ischaemic cardiac pathology.

European Journal of Trauma and Emergency SurgeryVol. 51(1)
John Hunter Hospital (AU), Hunter Medical Research Institute (AU), University of Newcastle Australia (AU)
Newcastle University
Good health and well-being
Openalex Percentile: Top 17%
Cardiac Arrest and Resuscitation
2.25
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