Vascular remodeling and TSLP/angiogenin overexpression in severe mixed asthma
The severe or frequent exacerbator asthmatics with bronchial mixed inflammatory profile are characterized by increased number of vessels and overexpression of TSLP and angiogenin, suggesting a pathogenetic link between mixed eosinophilic and neutrophilic inflammation and vascular remodeling.
Authors
- Vitina Carriero (ORCID: https://orcid.org/0000-0003-1866-5206)
- Elisa Arrigo (ORCID: https://orcid.org/0000-0003-1976-7466)
- Isabella Gnemmi (ORCID: https://orcid.org/0000-0003-0045-6369)
- Stefano Pizzimenti (ORCID: https://orcid.org/0000-0001-7723-8859)
- Fabio Luigi Massimo Ricciardolo (ORCID: https://orcid.org/0000-0003-1826-5018)
- Giuseppe Guida (ORCID: https://orcid.org/0000-0003-3876-8587)
- Stefano Levra (ORCID: https://orcid.org/0000-0002-5745-7701)
- Mirella Profita (ORCID: https://orcid.org/0000-0002-7821-8283)
- Antonino Di Stefano (ORCID: https://orcid.org/0000-0003-3479-0875)
- Francesca Bertolini (ORCID: https://orcid.org/0000-0003-4390-0394)
Institutions
- National Academies of Sciences, Engineering, and Medicine (US)
- Istituti Clinici Scientifici Maugeri (IT)
- Istituto di Farmacologia Traslazionale (IT)
- National Research Council (IT)
- Ospedale San Luigi Gonzaga (IT)
- University of Turin (IT)
Publication Details
- Journal
- Respiratory Research
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12931-025-03133-9
- Citations
- 3
- Primary Topic
- Asthma and respiratory diseases
- Type
- article
- Field-Weighted Citation Impact
- 3.49