Molecular epidemiology of Escherichia coli in bloodstream infections from a general hospital in Ningxia, China, 2022–2023
In our hospital, E. coli was resistant to most commonly used antibiotics, and cefoperazone/sulbactam, cefotetan, amikacin, and tigecycline were empirically selected for the treatment of bloodstream infections. The predominant ESBL genotype in our hospital was bla<sub>CTX-M</sub> and the major quinolone resistance gene was aac(6')-Ib-cr. Clonal relationship analysis revealed genetic diversity among the isolates.
Authors
- Wei-Zhen Hong (ORCID: https://orcid.org/0000-0002-4199-9354)
- Jia Wei (ORCID: https://orcid.org/0000-0001-9621-529X)
- Lixin Yan
- Liru Wang (ORCID: https://orcid.org/0000-0001-9705-3560)
- Wen Wang (ORCID: https://orcid.org/0000-0002-0419-1508)
- Gang� Li (ORCID: https://orcid.org/0000-0003-3875-2112)
- Tao Jia (ORCID: https://orcid.org/0000-0003-0536-966X)
- Xinxin Hu (ORCID: https://orcid.org/0009-0004-6427-020X)
Institutions
- Ningxia Medical University (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- BMC Infectious Diseases
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s12879-025-10658-3
- Citations
- 2
- Primary Topic
- Antibiotic Resistance in Bacteria
- Type
- article
- Field-Weighted Citation Impact
- 1.18