Dermatomyositis as a Paraneoplastic Syndrome in Cases of Aggressive Cervical Cancer

Dermatomyositis is an inflammatory myopathy characterized by proximal muscle weakness with concurrent cutaneous manifestations. Diagnosis is often made by the clinical presentation in conjunction with elevated muscle enzymes, serology, electromyogram findings, and muscle biopsy. Dermatomyositis is frequently complicated due to its known correlation with underlying malignancy, even if not diagnosed at the time of presentation. Timely treatment and screening strategies can help to improve patient outcomes and both quality and quantity of life. In this study, we describe a female diagnosed with dermatomyositis who unfortunately had rapid progression and development of invasive squamous cell carcinoma of the cervix.

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Publication Details

Journal
Cureus
Published
2025-02-28
DOI
https://doi.org/10.7759/cureus.79838
Primary Topic
Inflammatory Myopathies and Dermatomyositis
Type
article
Field-Weighted Citation Impact
0.00
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article

Dermatomyositis as a Paraneoplastic Syndrome in Cases of Aggressive Cervical Cancer

Kathryn Williams, Maria Carmona-Gonzalez
Cureus
Inflammatory Myopathies and Dermatomyositis
article

Dermatomyositis as a Paraneoplastic Syndrome in Cases of Aggressive Cervical Cancer

Kathryn Williams, Maria Carmona-Gonzalez
article en

Abstract

Dermatomyositis is an inflammatory myopathy characterized by proximal muscle weakness with concurrent cutaneous manifestations. Diagnosis is often made by the clinical presentation in conjunction with elevated muscle enzymes, serology, electromyogram findings, and muscle biopsy. Dermatomyositis is frequently complicated due to its known correlation with underlying malignancy, even if not diagnosed at the time of presentation. Timely treatment and screening strategies can help to improve patient outcomes and both quality and quantity of life. In this study, we describe a female diagnosed with dermatomyositis who unfortunately had rapid progression and development of invasive squamous cell carcinoma of the cervix.

CureusVol. 17(2)
Pensacola State College (US), Pensacola Historical Society (US), University of West Florida (US)
Good health and well-being
Openalex Percentile: Top 94%
Inflammatory Myopathies and Dermatomyositis
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