Molecular profiling of zoonotic hookworms infecting wild felids in northern Indiap

mortality.Among the VGs, feoB was possessed by 83% of the isolates followed by kpsMTIII (73%), fimH (70%), iutA (59%), and others.The most frequent combination observed was feoB + fimH (68%).However, correlation between 30-day mortality & possession of feoB + fimH combination.was statistically insignificant (p = 0.12).Discussion: The finding of 23% thirty-day mortality in our study was comparable to a similar study from Europe (2021) where the probability of death was 19.5% and.there was a strong positive correlation with the virulence genes.In our study, although majority had single or combination genes but the correlation was not significant which could be due to small sample size.Conclusion: All isolates possessed differentVGs encoding multiple virulence factors and > 50% mortality were associated with feoB + fimH combination.This knowledge may be useful for detecting virulent strains and predicting clinical outcome in E.coli BSI.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1016/j.ijid.2024.107667
Primary Topic
Zoonotic diseases and public health
Type
article
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article

Molecular profiling of zoonotic hookworms infecting wild felids in northern Indiap

Dhabaleswar K. Panda, Deepak Garg, D. Ram, Dr Thangam Venkatesan et al.
International Journal of Infectious Diseases
Zoonotic diseases and public health
article

Molecular profiling of zoonotic hookworms infecting wild felids in northern Indiap

Dhabaleswar K. Panda, Deepak Garg, D. Ram, Dr Thangam Venkatesan, Dr Anil Kumar Nehra, Dr M Karikalan, Dr Devendra Prasad Pateer, Dr Shamli, Dr A. M Pawde
article en

Abstract

mortality.Among the VGs, feoB was possessed by 83% of the isolates followed by kpsMTIII (73%), fimH (70%), iutA (59%), and others.The most frequent combination observed was feoB + fimH (68%).However, correlation between 30-day mortality & possession of feoB + fimH combination.was statistically insignificant (p = 0.12).Discussion: The finding of 23% thirty-day mortality in our study was comparable to a similar study from Europe (2021) where the probability of death was 19.5% and.there was a strong positive correlation with the virulence genes.In our study, although majority had single or combination genes but the correlation was not significant which could be due to small sample size.Conclusion: All isolates possessed differentVGs encoding multiple virulence factors and > 50% mortality were associated with feoB + fimH combination.This knowledge may be useful for detecting virulent strains and predicting clinical outcome in E.coli BSI.

International Journal of Infectious DiseasesVol. 152
Openalex Percentile: Top 95%
Zoonotic diseases and public health
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