Molecular profiling of zoonotic hookworms infecting wild felids in northern Indiap
mortality.Among the VGs, feoB was possessed by 83% of the isolates followed by kpsMTIII (73%), fimH (70%), iutA (59%), and others.The most frequent combination observed was feoB + fimH (68%).However, correlation between 30-day mortality & possession of feoB + fimH combination.was statistically insignificant (p = 0.12).Discussion: The finding of 23% thirty-day mortality in our study was comparable to a similar study from Europe (2021) where the probability of death was 19.5% and.there was a strong positive correlation with the virulence genes.In our study, although majority had single or combination genes but the correlation was not significant which could be due to small sample size.Conclusion: All isolates possessed differentVGs encoding multiple virulence factors and > 50% mortality were associated with feoB + fimH combination.This knowledge may be useful for detecting virulent strains and predicting clinical outcome in E.coli BSI.
Authors
- Dhabaleswar K. Panda (ORCID: https://orcid.org/0000-0002-0356-1781)
- Deepak Garg (ORCID: https://orcid.org/0000-0002-0888-3093)
- D. Ram
- Dr Thangam Venkatesan
- Dr Anil Kumar Nehra
- Dr M Karikalan
- Dr Devendra Prasad Pateer
- Dr Shamli
- Dr A. M Pawde
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.ijid.2024.107667
- Primary Topic
- Zoonotic diseases and public health
- Type
- article
- Field-Weighted Citation Impact
- 0.00