Community burden of Respiratory Viruses infections during influenza seasons from 2016/2017 to 2023/2024, Apulia region (Southern Italy)

vealed genetically diverse isolates without clusters of epidemiologically and genetically linked cases.20 different capsule-encoding loci (KL) were identified, the most common being KL64, KL17 and KL1 accounting for 32 (46%), 8 (12%) and 5 (7%) confirmed KpID cases, respectively.7 lipopolysaccharide-encoding loci (O loci) were identified with a predominance of O1/O2V1 (67%) and O1/O2V2 (19%).Discussion: These observations demonstrate the magnitude of the morbidity and mortality associated with KpID.Conclusion: Rapid identification of patients with invasive antimicrobial-resistant KpID is imperative in order to treat patients appropriately and timeously.The rise of AMR together with a limited antibiotic pipeline has piqued interest in the use of vaccines to prevent KpID in at-risk adults.