Clinico bacteriological profile of Empyema thoracis and its outcome

vealed genetically diverse isolates without clusters of epidemiologically and genetically linked cases.20 different capsule-encoding loci (KL) were identified, the most common being KL64, KL17 and KL1 accounting for 32 (46%), 8 (12%) and 5 (7%) confirmed KpID cases, respectively.7 lipopolysaccharide-encoding loci (O loci) were identified with a predominance of O1/O2V1 (67%) and O1/O2V2 (19%).Discussion: These observations demonstrate the magnitude of the morbidity and mortality associated with KpID.Conclusion: Rapid identification of patients with invasive antimicrobial-resistant KpID is imperative in order to treat patients appropriately and timeously.The rise of AMR together with a limited antibiotic pipeline has piqued interest in the use of vaccines to prevent KpID in at-risk adults.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1016/j.ijid.2024.107526
Primary Topic
Pleural and Pulmonary Diseases
Type
article
Field-Weighted Citation Impact
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article

Clinico bacteriological profile of Empyema thoracis and its outcome

Dr Manimaran Marappan
International Journal of Infectious Diseases
Pleural and Pulmonary Diseases
article

Clinico bacteriological profile of Empyema thoracis and its outcome

Dr Manimaran Marappan
article en

Abstract

vealed genetically diverse isolates without clusters of epidemiologically and genetically linked cases.20 different capsule-encoding loci (KL) were identified, the most common being KL64, KL17 and KL1 accounting for 32 (46%), 8 (12%) and 5 (7%) confirmed KpID cases, respectively.7 lipopolysaccharide-encoding loci (O loci) were identified with a predominance of O1/O2V1 (67%) and O1/O2V2 (19%).Discussion: These observations demonstrate the magnitude of the morbidity and mortality associated with KpID.Conclusion: Rapid identification of patients with invasive antimicrobial-resistant KpID is imperative in order to treat patients appropriately and timeously.The rise of AMR together with a limited antibiotic pipeline has piqued interest in the use of vaccines to prevent KpID in at-risk adults.

International Journal of Infectious DiseasesVol. 152
Zero hunger
Openalex Percentile: Top 94%
Pleural and Pulmonary Diseases
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