Molecular monitoring of RNA viruses belonging to Orthohantaviridae family circulating among small mammals in two regions of the Russian Federation

mortality.Among the VGs, feoB was possessed by 83% of the isolates followed by kpsMTIII (73%), fimH (70%), iutA (59%), and others.The most frequent combination observed was feoB + fimH (68%).However, correlation between 30-day mortality & possession of feoB + fimH combination.was statistically insignificant (p = 0.12).Discussion: The finding of 23% thirty-day mortality in our study was comparable to a similar study from Europe (2021) where the probability of death was 19.5% and.there was a strong positive correlation with the virulence genes.In our study, although majority had single or combination genes but the correlation was not significant which could be due to small sample size.Conclusion: All isolates possessed differentVGs encoding multiple virulence factors and > 50% mortality were associated with feoB + fimH combination.This knowledge may be useful for detecting virulent strains and predicting clinical outcome in E.coli BSI.