Species distribution, antibiotic susceptibility and clinical characteristics in Enterococcal bacteremia; experience from South India
the bacteria within the first hour of treatment as compared to the 12 hours taken by VCM.The in vivo systemic infection in BALB/c mice reduced MRSA infection in the kidney, liver, and blood by 13fold, 19.7-fold, and 2.7-fold, respectively.Discussions: These studies confirm VCM-AMP-PEP's as an alternative treatment for drug-resistant infections.Conclusion: VCM-AMP-PEP exhibits superior efficacy over VCM alone against drug-resistant bacteria and expanded its activity to gram negatives, showcasing the potential of this nanoformulation for treating infections caused by resistant strains.
Authors
- Dr Vettakkara Niyas
- Dr Rajalakshmi Ananthanarayanan
- Dr Febeena Hussain
Institutions
- Kerala Institute of Medical Sciences (IN)
Publication Details
- Journal
- International Journal of Infectious Diseases
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.ijid.2024.107403
- Primary Topic
- Antimicrobial Resistance in Staphylococcus
- Type
- article
- Field-Weighted Citation Impact
- 0.00