Diagnostic Utility of Gene Expert MTB / RIF in Extra pulmonary koch's

the detection of NTM was low ( < 90%) but high ( 90%) for the detection of MTBC.In patients with a positive auramine O smear microscopy result, alternative diagnostic methods like molecular assays that can reliably detect and distinguish between MTBC and NTM in clinical samples should be considered while awaiting mycobacterial culture results.A negative auramine O smear microscopy result may be used to rule out the presence of MTBC but not NTM. Conclusion:The diagnostic utility of auramine O smear microscopy for detecting NTM and MTBC in clinical samples is limited by its poor sensitivity and PPV.These findings highlight the need for more accurate and reliable diagnostic techniques for detecting NTM and MTBC directly from clinical samples.

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Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1016/j.ijid.2024.107552
Primary Topic
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Type
article
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article

Diagnostic Utility of Gene Expert MTB / RIF in Extra pulmonary koch's

Dr Manimaran Marappan, Dr Suresh Sagadevan
International Journal of Infectious Diseases
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
article

Diagnostic Utility of Gene Expert MTB / RIF in Extra pulmonary koch's

Dr Manimaran Marappan, Dr Suresh Sagadevan
article en

Abstract

the detection of NTM was low ( < 90%) but high ( 90%) for the detection of MTBC.In patients with a positive auramine O smear microscopy result, alternative diagnostic methods like molecular assays that can reliably detect and distinguish between MTBC and NTM in clinical samples should be considered while awaiting mycobacterial culture results.A negative auramine O smear microscopy result may be used to rule out the presence of MTBC but not NTM. Conclusion:The diagnostic utility of auramine O smear microscopy for detecting NTM and MTBC in clinical samples is limited by its poor sensitivity and PPV.These findings highlight the need for more accurate and reliable diagnostic techniques for detecting NTM and MTBC directly from clinical samples.

International Journal of Infectious DiseasesVol. 152
St. James's Hospital (IE)
Zero hunger
Openalex Percentile: Top 94%
Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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