Clinical characteristics and a changing trend of antimicrobial susceptibility pattern of Streptococcus suis infection at Siriraj Hospital: a 16-year retrospective study

vealed genetically diverse isolates without clusters of epidemiologically and genetically linked cases.20 different capsule-encoding loci (KL) were identified, the most common being KL64, KL17 and KL1 accounting for 32 (46%), 8 (12%) and 5 (7%) confirmed KpID cases, respectively.7 lipopolysaccharide-encoding loci (O loci) were identified with a predominance of O1/O2V1 (67%) and O1/O2V2 (19%).Discussion: These observations demonstrate the magnitude of the morbidity and mortality associated with KpID.Conclusion: Rapid identification of patients with invasive antimicrobial-resistant KpID is imperative in order to treat patients appropriately and timeously.The rise of AMR together with a limited antibiotic pipeline has piqued interest in the use of vaccines to prevent KpID in at-risk adults.

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Journal
International Journal of Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1016/j.ijid.2024.107525
Primary Topic
Streptococcal Infections and Treatments
Type
article
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article

Clinical characteristics and a changing trend of antimicrobial susceptibility pattern of Streptococcus suis infection at Siriraj Hospital: a 16-year retrospective study

Dr Anupop Jitmuang, Dr Chittamas Panpaeng, Dr Wichuda Kamolvit
International Journal of Infectious Diseases
Streptococcal Infections and Treatments
article

Clinical characteristics and a changing trend of antimicrobial susceptibility pattern of Streptococcus suis infection at Siriraj Hospital: a 16-year retrospective study

Dr Anupop Jitmuang, Dr Chittamas Panpaeng, Dr Wichuda Kamolvit
article en

Abstract

vealed genetically diverse isolates without clusters of epidemiologically and genetically linked cases.20 different capsule-encoding loci (KL) were identified, the most common being KL64, KL17 and KL1 accounting for 32 (46%), 8 (12%) and 5 (7%) confirmed KpID cases, respectively.7 lipopolysaccharide-encoding loci (O loci) were identified with a predominance of O1/O2V1 (67%) and O1/O2V2 (19%).Discussion: These observations demonstrate the magnitude of the morbidity and mortality associated with KpID.Conclusion: Rapid identification of patients with invasive antimicrobial-resistant KpID is imperative in order to treat patients appropriately and timeously.The rise of AMR together with a limited antibiotic pipeline has piqued interest in the use of vaccines to prevent KpID in at-risk adults.

International Journal of Infectious DiseasesVol. 152
Mahidol University (TH)
Good health and well-being
Openalex Percentile: Top 95%
Streptococcal Infections and Treatments
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