Perturbative analysis of biological parameters for simulating glioblastoma multiforme using Swanson’s model by the method of symmetries

The present work aims to propose an exact solution through split and symmetries for a model used to simulate the growth rate of cancer cells in a specific region of the human body, it also intends to study the behavior of the tumor cell concentration rate by varying the diffusion and proliferation coefficients randomly within a specified interval. The model utilized to simulate the cellgrowth rate is the Swanson model, disregarding the term that follows the treatment and considering a constant diffusion coefficient per region. Attaining the exact solution of the Swanson model can aid in the treatment of specific cancer types, as implementing a more accurate model leads to a decrease in the destruction rate of healthy cells neighboring the cancerous cells.

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Journal
Ciência e Natura
Published
2024-11-07
DOI
https://doi.org/10.5902/2179460x87204
Primary Topic
Mathematical Biology Tumor Growth
Type
article
Field-Weighted Citation Impact
0.00

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article

Perturbative analysis of biological parameters for simulating glioblastoma multiforme using Swanson’s model by the method of symmetries

Cláudio Zen Petersen, Fernanda Tumelero, Aquiles Almeida Ribeiro, Jorge Luiz de Mello Caurio
Ciência e Natura
Mathematical Biology Tumor Growth
article

Perturbative analysis of biological parameters for simulating glioblastoma multiforme using Swanson’s model by the method of symmetries

Cláudio Zen Petersen, Fernanda Tumelero, Aquiles Almeida Ribeiro, Jorge Luiz de Mello Caurio
article en

Abstract

The present work aims to propose an exact solution through split and symmetries for a model used to simulate the growth rate of cancer cells in a specific region of the human body, it also intends to study the behavior of the tumor cell concentration rate by varying the diffusion and proliferation coefficients randomly within a specified interval. The model utilized to simulate the cellgrowth rate is the Swanson model, disregarding the term that follows the treatment and considering a constant diffusion coefficient per region. Attaining the exact solution of the Swanson model can aid in the treatment of specific cancer types, as implementing a more accurate model leads to a decrease in the destruction rate of healthy cells neighboring the cancerous cells.

Ciência e NaturaVol. 46(esp. 1)
Universidade Federal do Rio Grande (BR), Universidade Federal de Pelotas (BR)
Coordenação de Aperfeiçoamento de Pessoal de Nível Superior
Openalex Percentile: Top 72%
Mathematical Biology Tumor Growth
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Perturbative analysis of biological parameters for simulating glioblastoma multiforme using Swanson’s model by the method of symmetries — Cláudio Zen Petersen, Fernanda Tumelero, et al. · Ciência e Natura (2024) | TGRS Research Map | TGRS