Exploring Phage-Antibiotic Synergies in The Context of Biofilm-related Infectious Diseases

for general hospitals.There was, no significant difference among the individual facilities (p = 0.0816), by level of care (p = 1.039), or by ownership (0.9617).The intention to prescribe antibiotics was inclined towards intrinsic factors of the individual clinician such as access to information during pre-service and in-service training, approval by their colleagues and seniors, perceived risks to the patient and their perceived ability to address irrational antibiotic use and their attitude towards change given the environment in which they work.The extrinsic factors fostered by the facility and the health system at large included: availability of diagnostic services, availability platforms for continuous medical education, availability of enough staff to manage the patient load.Discussion: Current interventions to address AMR involve creating awareness among clinicians.However, the clinician's ability to treat a patient based on the knowledge acquired in medical school, during their practice as well as the availability and access to the required diagnostics and antibiotics are major factors influencing their prescribing behaviour. Conclusion:The irrational use of antibiotics in health facilities in Central Uganda is high despite high levels of awareness of antimicrobial resistance among clinicians.The interventions to improve rational antibiotic use should be specific to a facility and more so to the individual clinicians' behaviour.

Authors

Publication Details

Journal
International Journal of Infectious Diseases
Published
2025-02-28
DOI
https://doi.org/10.1016/j.ijid.2024.107590
Citations
2
Primary Topic
Bacteriophages and microbial interactions
Type
article
Field-Weighted Citation Impact
3.43
Controls
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article

Exploring Phage-Antibiotic Synergies in The Context of Biofilm-related Infectious Diseases

Professor Rob Lavigne, Daniël De Vos, Jean‐Paul Pirnay, Maya Merabishvilli et al.
2 citations
International Journal of Infectious Diseases
Bacteriophages and microbial interactions
3.43
article

Exploring Phage-Antibiotic Synergies in The Context of Biofilm-related Infectious Diseases

Professor Rob Lavigne, Daniël De Vos, Jean‐Paul Pirnay, Maya Merabishvilli, Dr Steven De Soir, Professor Françoise Van Bambeke, MSc Hortence Parée, Nur Hidayatul Nazirah Kumarudin, Jeroen Waegemans, Professor Annabel Braem
article en
2 citations

Abstract

for general hospitals.There was, no significant difference among the individual facilities (p = 0.0816), by level of care (p = 1.039), or by ownership (0.9617).The intention to prescribe antibiotics was inclined towards intrinsic factors of the individual clinician such as access to information during pre-service and in-service training, approval by their colleagues and seniors, perceived risks to the patient and their perceived ability to address irrational antibiotic use and their attitude towards change given the environment in which they work.The extrinsic factors fostered by the facility and the health system at large included: availability of diagnostic services, availability platforms for continuous medical education, availability of enough staff to manage the patient load.Discussion: Current interventions to address AMR involve creating awareness among clinicians.However, the clinician's ability to treat a patient based on the knowledge acquired in medical school, during their practice as well as the availability and access to the required diagnostics and antibiotics are major factors influencing their prescribing behaviour. Conclusion:The irrational use of antibiotics in health facilities in Central Uganda is high despite high levels of awareness of antimicrobial resistance among clinicians.The interventions to improve rational antibiotic use should be specific to a facility and more so to the individual clinicians' behaviour.

International Journal of Infectious DiseasesVol. 152
Zero hunger
Openalex Percentile: Top 10%
Bacteriophages and microbial interactions
3.43
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