Insights into the burden of bacterial antimicrobial resistance (AMR) in the WHO Eastern Mediterranean Region: a crucial step towards evidence-informed and targeted public health interventions

study, A. baumannii predominated, with 80% being MDR organisms.Polymicrobial and fungal BSIs occurred later during hospitalization, highlighting evolving infection patterns in burn patients.Since both gram-positive and gram-negative infections occurred early in the admission, with polymicrobial infections more common later, initial targeted narrow-spectrum antimicrobial use is not possible.Instead, antimicrobial de-escalation should be prioritized once culture results are available.Additionally, infection prevention protocols and proper wound care should be strictly adhered to, to reduce BSIs. Conclusion:Our findings emphasise the need to shift focus from treating BSIs to preventing them through wound care and infection control.Broad-spectrum antibiotics should be used judiciously and quickly de-escalated to minimise AMR development.