SPRY1 regulates macrophage M1 polarization in skin aging and melanoma prognosis
SPRY1 accelerates skin aging by promoting macrophage M1 polarization and may serve as a promising therapeutic target. Future research should focus on in vivo validation and further exploration of its regulatory networks to develop novel treatments.
Authors
- Senlin Xu (ORCID: https://orcid.org/0000-0001-6625-5370)
- Xiaofei Zhang (ORCID: https://orcid.org/0000-0001-6765-8411)
- Xie Han (ORCID: https://orcid.org/0000-0002-9690-0200)
- Xun Zhang (ORCID: https://orcid.org/0000-0001-6538-9473)
- Dan Lu
- Yingnan Geng
- Yanyun Cao
- Rongxin Zhao
- Yuqing Wang (ORCID: https://orcid.org/0009-0006-8271-418X)
Institutions
- Jiangsu University (CN)
- Second Military Medical University (CN)
- Shanghai Jiao Tong University (CN)
- Fudan University (CN)
- Xuzhou Cancer Hospital (CN)
- Tongren Hospital (CN)
- Shanghai Xuhui Central Hospital (CN)
- Pudong New Area People's Hospital (CN)
Publication Details
- Journal
- Translational Oncology
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1016/j.tranon.2025.102331
- Citations
- 2
- Primary Topic
- Immune cells in cancer
- Type
- article
- Field-Weighted Citation Impact
- 1.59