Rare Metastatic Clear Cell Renal Cell Carcinoma to Pancreas Revealed by 68Ga-FAPI PET/CT

A 56-year-old woman underwent surgery for clear cell renal cell carcinoma (ccRCC) 8 years ago. The patient incidentally discovered 2 foci in the body and tail of the pancreas by abdominal ultrasound during follow-up. MRI disclosed lesions with central inhomogeneous enhancement and restricted diffusion. The 2 lesions showed no 18 F-FDG uptake but had mild to moderate 68 Ga-FAPI accumulation in the PET/CT images. Postoperative pathology and immunohistochemical analysis confirmed metastatic ccRCC to the pancreas. 68 Ga-FAPI PET/CT might be a useful tool in the diagnosis and staging of ccRCC.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-02-28
DOI
https://doi.org/10.1097/rlu.0000000000005730
Primary Topic
Peptidase Inhibition and Analysis
Type
article
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article

Rare Metastatic Clear Cell Renal Cell Carcinoma to Pancreas Revealed by 68Ga-FAPI PET/CT

Xinming Zhao, Fenglian Jing, Jingmian Zhang, Yunuan Liu et al.
2 links
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
article

Rare Metastatic Clear Cell Renal Cell Carcinoma to Pancreas Revealed by 68Ga-FAPI PET/CT

Xinming Zhao, Fenglian Jing, Jingmian Zhang, Yunuan Liu, Yan Zhao
article en

Abstract

A 56-year-old woman underwent surgery for clear cell renal cell carcinoma (ccRCC) 8 years ago. The patient incidentally discovered 2 foci in the body and tail of the pancreas by abdominal ultrasound during follow-up. MRI disclosed lesions with central inhomogeneous enhancement and restricted diffusion. The 2 lesions showed no 18 F-FDG uptake but had mild to moderate 68 Ga-FAPI accumulation in the PET/CT images. Postoperative pathology and immunohistochemical analysis confirmed metastatic ccRCC to the pancreas. 68 Ga-FAPI PET/CT might be a useful tool in the diagnosis and staging of ccRCC.

Clinical Nuclear MedicineVol. 50(10)
Hebei Medical University (CN), Fourth Hospital of Hebei Medical University (CN)
Good health and well-being
Openalex Percentile: Top 95%
Peptidase Inhibition and Analysis
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