Umbilical cord blood-derived platelet-rich plasma as a coating substrate supporting cell adhesion and biological activities of wound healing
UCB-derived PrP gels facilitate cell behaviours in vitro, including cell adhesion, growth, and migration. In addition, in animal models, UCB-derived PrP reduced the wound healing time and enhanced the completion of skin tissues by increasing granulation tissue formation and reducing neutrophils at wound sites. These UCB-derived PrP gels will be used to support spheroid formation that will be used as biomaterials for 3D printing, engraftment, and wound healing treatment.
Authors
- Nguyen Thu Huyen (ORCID: https://orcid.org/0000-0002-5053-5682)
- Uyen Thi Trang Than (ORCID: https://orcid.org/0000-0002-2847-7068)
- Xuan-Hai Do (ORCID: https://orcid.org/0000-0002-8017-4195)
- Hoang Thi My Nhung (ORCID: https://orcid.org/0000-0003-1717-1570)
- Xuan-Hung Nguyen
- Quang-Dung Le
- Thanh-Hai Tong (ORCID: https://orcid.org/0009-0000-9711-2663)
- Nam Hoang Nguyen (ORCID: https://orcid.org/0000-0003-2780-8336)
- Thanh-Thao Nguyen
- Bich-Hanh Pham
Institutions
- Vietnam National University, Hanoi (VN)
- Vietnam Military Medical University (VN)
- VinUniversity (VN)
- VNU University of Science (VN)
Publication Details
- Journal
- European journal of medical research
- Published
- 2025-02-28
- DOI
- https://doi.org/10.1186/s40001-025-02388-8
- Citations
- 3
- Primary Topic
- Periodontal Regeneration and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 5.51