Dl-3-n-butylphthalide ameliorates diabetic foot ulcer by inhibiting apoptosis and promoting angiogenesis
This study found that NBP could treat DFU by decreasing the rate of apoptosis and increasing angiogenesis <i>via</i> the advanced glycation end products-receptor of advanced glycation end products signaling pathway and binding to the heme oxygenase 1, caspase 3, B cell leukemia/lymphoma 2, brain derived neurotrophic factor, and nuclear factor erythroid 2 L2 genes.
Authors
- Peisheng Jin (ORCID: https://orcid.org/0000-0002-2239-0156)
- Wuhan Wei (ORCID: https://orcid.org/0000-0002-2096-3870)
- Qiang Li (ORCID: https://orcid.org/0000-0002-5289-0709)
- Dong Zhu (ORCID: https://orcid.org/0000-0002-3241-2996)
- Qichuan Yin
- Caiqi Shen
- Yanqin Bai (ORCID: https://orcid.org/0000-0002-6038-0805)
- Jingyu Zhang (ORCID: https://orcid.org/0000-0002-5629-9246)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Peking Union Medical College Hospital (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-02-28
- DOI
- https://doi.org/10.4239/wjd.v16.i4.101916
- Citations
- 1
- Primary Topic
- Neurological Disease Mechanisms and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.84