MiR-29a-3p inhibits fibrosis of diabetic kidney disease in diabetic mice <i>via</i> downregulation of DNA methyl transferase 3A and 3B
MiR-29a-3p can regulate Wnt/β-catenin and Janus kinase/signal transducer and activator of transcription signal pathways by regulating and inhibiting the expression of DNMT3A/3B and thus participate in the inhibition of DKD-related fibrosis.
Authors
- Jianying Tang
- Ying Yang (ORCID: https://orcid.org/0000-0001-5753-7106)
- Guiqing Li (ORCID: https://orcid.org/0000-0002-4598-1522)
- Jian Chen (ORCID: https://orcid.org/0000-0001-5230-7141)
- Bing Feng (ORCID: https://orcid.org/0000-0002-9453-2969)
- Jiao Mu (ORCID: https://orcid.org/0009-0002-4402-0241)
- Yi Chen (ORCID: https://orcid.org/0000-0002-5180-3490)
Institutions
- Army Medical University (CN)
- Chongqing Medical University (CN)
Publication Details
- Journal
- World Journal of Diabetes
- Published
- 2025-02-28
- DOI
- https://doi.org/10.4239/wjd.v16.i4.93630
- Citations
- 4
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 3.22